Anyone wishing to reduce wrinkles should not rely on a single active ingredient, but on a consistent anti-aging routine with effective serums, sufficient moisture and daily sun protection. Retinoids, hyaluronic acid, vitamin C and peptides are particularly relevant.

Retinol is one of the most thoroughly researched active ingredients in anti-aging skincare and, when used regularly, can support skin renewal and collagen synthesis. Hyaluronic acid binds intensive moisture and can visibly plump dehydration lines in particular. Vitamin C provides antioxidant protection against free radicals, while peptides specifically address different processes relevant to skin texture, elasticity and expression lines.

Consistent UV protection is equally important. UVA radiation contributes significantly to premature skin aging. A day cream with SPF 50+ should therefore be an integral part of every wrinkle-focused skincare routine.

The best skincare against wrinkles combines several mechanisms of action instead of relying exclusively on a wrinkle cream.

An effective anti-aging routine can look like this:

Morning:
Cleansing → Tonic → Vit C + Spilanthol Serum + Hyper Hyaluron Serum → Eye Care → Four Seasons Day Cream LSF 50+

Evening:
Cleansing → Tonic → Platinum Elixir → depending on your skin and experience with retinol, Retinol Sensitive or Retinol Intense → Time Machine

What matters is not the number of products, but a sensible combination of high-quality active ingredients and their consistent use.

There is no single best serum for wrinkles, as different active ingredients address different causes of visible skin aging.

The Hyper Hyaluron Serum combines intensive hydration with the neuroactive peptides Argireline® and SYN®-AKE. In an instrumental assessment using PRIMOS® High-Res., the measured wrinkle depth was reduced by an average of 17 % after 28 days.

The Vit C + Spilanthol Serum combines 20 % vitamin C, including in the form of Et-VC®, with spilanthol. After 28 days, an average reduction in wrinkle depth of around 16 % was measured.

The Collagen Serum is particularly suitable for declining firmness and dry or mature skin. In addition to soluble collagen, it contains the signal peptide complex Matrixyl™ 3000, which is specifically designed to support skin structure and elasticity.

The Platinum Elixir complements a sophisticated anti-aging routine, especially when diminished radiance, oxidative stress, and a tired-looking complexion are a focus alongside wrinkles. The formula with platinum, Clarivine™, and lycopene is designed to provide antioxidant support and improve the skin's radiance.

For comprehensive facial skincare against wrinkles, these serums can be combined purposefully depending on skin condition, time of day, and tolerance.

With a cream for wrinkles, too, the overall formula is more decisive than any single supposed anti-aging active ingredient.

For nighttime, the Time Machine was developed as comprehensive anti-aging night care. It combines, among other ingredients, hyaluronic acid, collagen, antioxidant active ingredients, skin-identical lipids, and innovative active-ingredient technologies.

During the day, protection is particularly important: the Four Seasons Day Cream with SPF 50+ combines facial skincare with high UVA and UVB protection. As UV radiation is one of the most important external factors in premature skin aging, daily sun protection is among the most effective measures for counteracting the development of new wrinkles.

Retinol and hyaluronic acid work differently and therefore complement each other ideally.

Hyaluronic acid binds moisture and makes dehydrated skin and fine lines caused by dryness appear plumper and smoother in particular. It is therefore ideal for daily hydration.

Retinol, on the other hand, acts more strongly on structural signs of skin aging. Retinoids can support skin renewal, promote collagen synthesis, and, with regular use, visibly improve fine lines and wrinkles.

If you have no experience with retinoids yet or have sensitive skin, you can start with Retinol Sensitive. The Retinol Intense was developed for skin experienced with retinol.

You can also find more information on correct use in our article “Does Retinol Make the Skin Thinner?”.

Vitamin C is one of the most important antioxidants in modern anti-aging skincare. It protects the skin from oxidative stress and also plays a role in the body's own collagen synthesis.

The Vit C + Spilanthol Serum by DOC BERGER EFFECT contains 20 % vitamin C and, among other ingredients, the stabilized vitamin C derivative Et-VC®. The formula also contains spilanthol, which is used in particular to care for facial areas affected by facial expressions.

In an instrumental assessment of the finished serum, an average reduction in wrinkle depth of around 16 % was measured after 28 days.

Vitamin C is therefore particularly interesting when pigmentation spots, UV-induced skin aging, or an uneven complexion are to be addressed alongside wrinkles.

Peptides are among the most exciting active ingredients in modern facial skincare for wrinkles. However, one thing is important: not all peptides are the same.

So-called neuropeptides such as Argireline® or SYN®-AKE are primarily used for expression lines. They are therefore particularly interesting for forehead lines, frown lines, and crow's feet.

Signal peptides take a different approach. The peptide complex Matrixyl™ 3000, for example, is used to support processes involved in the skin matrix, collagen structure, and elasticity.

The Hyper Hyaluron Serum combines hyaluronic acid with Argireline® and SYN®-AKE, while the Collagen Serum contains Matrixyl™ 3000, among other ingredients.

Even pronounced or deep wrinkles generally cannot be completely removed by cosmetics. However, high-quality active cosmetic care can help visibly improve wrinkle depth, skin texture, moisture levels, and firmness.

A combination of different approaches is particularly useful: retinoids for long-term skin structure, hyaluronic acid for intensive moisture binding, vitamin C and other antioxidants to protect against oxidative stress, and peptides for different aspects of facial expressions and the skin matrix.

Realistic expectations are important. Cosmetic active ingredients differ fundamentally from invasive treatments such as botulinum toxin or fillers. However, they can be used daily and thus contribute in the long term to visibly smoother, more cared-for-looking skin.

If you would like to combine different groups of active ingredients, you can find further information in our article on the most important anti-aging active ingredients.

The skin around the eyes is particularly thin and has fewer sebaceous glands than many other areas of the face. Moisture loss, facial expressions and UV radiation can therefore become visible around the eyes at an early stage.

Lifting Eye Wonder was developed specifically for this sensitive area. The formulation combines, among other ingredients, hyaluronic acid, caffeine, antioxidants and the peptide Argireline®, targeting fine lines, crow’s feet, puffiness and a tired-looking eye area.

The same applies around the eyes: it is not only about reducing existing eye wrinkles, but also about counteracting their more pronounced development as early as possible. This includes consistent eye care, sufficient moisture and daily sun protection.

There is no specific age at which anti-aging skincare for wrinkles suddenly becomes necessary. Skin aging develops gradually and is influenced by factors including genetics, UV radiation, facial expressions, lifestyle and individual skin condition.

Preventive measures such as antioxidant skincare, sufficient moisture and, in particular, daily UV protection are therefore worthwhile even before pronounced wrinkles become visible.

As signs of skin aging increase, more targeted active ingredients such as retinoids, vitamin C and peptides can be added. What matters less is biological age than the skin’s current condition.

Starting early does not necessarily mean using a particularly aggressive routine. In the long term, a well-balanced, consistent skincare routine is usually more beneficial than using as many highly concentrated active ingredients as possible at the same time.