NOVORETIN™

NOVORETIN™

September 22 2025 – Dr. Luise Berger

1. DESCRIPTION OF NOVORETIN™

NovoRetin™ is an innovative, plant-based active considered a natural retinol alternative. It is specifically designed to mimic the positive effects of classical retinoids – but without their typical side effects such as redness, dryness, or flaking.

Derived from the Pistacia Lentiscus (mastic tree), NovoRetin™ is known for its ability to increase endogenous retinoic acid concentration in the skin. This enables it to deliver effects comparable to retinol – but in a much gentler and more tolerable way.

2. BENEFITS OF NOVORETIN™

• Naturally increases retinoic acid concentration in the skin
• Stimulates collagen production and improves skin elasticity
• Visibly reduces wrinkles and fine lines
• Promotes a more even complexion by brightening pigmentation spots
• Provides antioxidant and anti-inflammatory protection against environmental stress

3. USES OF NOVORETIN™

NovoRetin™ is used in modern anti-aging serums and creams. Thanks to its excellent tolerability, it is particularly suitable for people with sensitive skin who want to benefit from the effects of classical retinoids while avoiding unwanted side effects.

4. SKIN CONCERNS NOVORETIN™ CAN ADDRESS

• Wrinkles and fine lines
• Pigmentation spots and sun damage
• Loss of skin elasticity
• Sensitive skin that does not tolerate retinol well
• Skin requiring protection from oxidative stress

WHAT IS NOVORETIN™?

NovoRetin™ is an innovative anti-aging active, developed as a natural and well-tolerated alternative to retinol. Its unique feature lies in its ability to increase the endogenous retinoic acid concentration in the skin – boosting the body’s own retinoic acid levels without the need for direct application of classical retinol or retinoic acid. As a result, NovoRetin™ can achieve comparable effects but without the typical side effects such as redness, dryness, or flaking.

The active is derived from the Pistacia Lentiscus (mastic tree), known for its regenerative and antioxidant properties. Through modern biotechnological processes, this natural origin has been transformed into a high-performance ingredient that captures the benefits of classical retinoids while avoiding their drawbacks.

Clinical studies have shown that NovoRetin™ stimulates collagen production, smooths skin texture, and visibly improves the appearance of wrinkles, pigmentation spots, and blemishes.

Unlike retinol, NovoRetin™ does not need to be converted into retinoic acid. Instead, it directly modulates retinoid-like signaling pathways, resulting in faster, more effective, and better-tolerated performance – ideal for sensitive skin types or users who have not been able to tolerate retinol in the past.

NATURAL SOURCES AND PRODUCTION OF NOVORETIN™

Natural origin: NovoRetin™ is obtained from the resin of the mastic tree (Pistacia Lentiscus), traditionally valued for its healing and skin-caring properties.
Biotechnological development: Innovative processes have created an active that harnesses natural mechanisms to enhance retinoid signaling activity in the skin.
High tolerability: Unlike retinol, NovoRetin™ causes little to no irritation, making it suitable even for sensitive skin types.
Stable formulation: The active is less prone to degradation by light or oxygen, ensuring longer-lasting efficacy in cosmetic formulations.

By combining the strength of classical retinoids with the gentleness of next-generation actives, NovoRetin™ represents a breakthrough for those seeking maximum anti-aging efficacy with superior tolerability.

BENEFITS OF NOVORETIN™ IN SKINCARE

EFFECTIVE WRINKLE REDUCTION WITH NOVORETIN™

NovoRetin™ increases the endogenous retinoic acid concentration in the skin and activates the same signaling pathways as classical retinol. The result: a visible reduction of fine lines and wrinkles – without the typical side effects of conventional retinoids.

GENTLE AND TOLERABLE RETINOL ALTERNATIVE WITH NOVORETIN™

Many users react sensitively to retinol. NovoRetin™ offers a skin-friendly alternative that delivers comparable results while causing significantly less irritation, redness, or flaking.

CLINICALLY PROVEN EFFICACY OF NOVORETIN™

Studies have shown that NovoRetin™ stimulates collagen production, improves skin elasticity, and refines skin texture. At the same time, it reduces pigmentation spots and promotes a more even complexion.

VERSATILE USE OF NOVORETIN™ IN SKINCARE

NovoRetin™ is incorporated into anti-aging serums and creams and is suitable for a variety of skin types, including sensitive skin. It effectively targets wrinkles, pigmentation spots, sun damage, and supports overall skin regeneration.

SUPPORTING SKIN HEALTH WITH NOVORETIN™

Beyond its anti-aging benefits, NovoRetin™ helps strengthen the skin barrier, reduce oxidative stress, and improve long-term skin resilience and health.

NOVORETIN™ FOR DIFFERENT SKIN CONDITIONS

The active ingredient NovoRetin™, derived from the resin of the mastic tree, is considered a natural retinol alternative with outstanding tolerability. It activates retinoid-like signaling pathways, increases the skin’s own retinoic acid concentration, and adapts to a variety of skin needs.

NOVORETIN™ FOR WRINKLES AND FINE LINES

NovoRetin™ stimulates collagen production and reduces the depth of fine lines and wrinkles. Especially in the forehead and eye area, it helps create a smoother, firmer skin appearance.

NOVORETIN™ FOR PREMATURE SKIN AGING

By stimulating cellular regeneration processes, NovoRetin™ helps slow down skin aging. It protects the skin against photoaging and contributes to maintaining a youthful, elastic appearance for longer.

NOVORETIN™ FOR DULL AND TIRED-LOOKING SKIN

NovoRetin™ supports cell renewal and restores radiance. The skin appears fresher, more vital, and develops a healthy glow.

NOVORETIN™ FOR SENSITIVE SKIN

Unlike traditional retinol, NovoRetin™ is significantly more tolerable. It is also suitable for sensitive skin types who have not been able to use retinoids before, offering a gentle way to benefit from retinoid-like actives.

NOVORETIN™ FOR OVERALL SKIN HEALTH

Regular use of products with NovoRetin™ promotes balanced, resilient skin. Beyond its anti-aging effects, it helps reduce pigmentation spots and strengthens the skin barrier.

NovoRetin™ thus represents a new generation of plant-based actives, combining anti-aging performance with high tolerability and versatile applications.

NOVORETIN™ IN DOC BERGER EFFECT PRODUCTS

NovoRetin™ is an integral part of the retinol serums by DOC BERGER EFFECT. It complements classical retinoids and enhances their efficacy while maintaining excellent skin tolerability. This makes it a perfect example of combining innovative anti-aging science with a gentle application suitable even for sensitive skin.

RETINOL SENSITIVE WITH NOVORETIN™

The Retinol Sensitive Serum was specifically developed for beginners in retinol care. By combining gently dosed retinol, NovoRetin™, and supportive actives, it provides an ideal balance between efficacy and tolerability:

• Stimulates collagen production and reduces early fine lines
• Improves skin texture and refines pores
• Protects sensitive skin from irritation and supports the skin barrier

This makes the serum the perfect choice for those seeking a gentle introduction to retinoid care while still expecting visible results.

RETINOL INTENSE WITH NOVORETIN™

The Retinol Intense Serum is designed for experienced retinol users seeking more intensive results. In this advanced formulation, NovoRetin™ enhances the effects of classic retinol, modern retinoids, and bakuchiol:

• Visibly reduces wrinkles and fine lines
• Brightens pigmentation spots and supports scar healing
• Regulates sebum production and combats blemishes
• Smooths skin texture and promotes a more even complexion

By incorporating NovoRetin™, the serum delivers its effects more precisely while maintaining high skin tolerability – a high-performance solution that combines anti-aging, skin clarification, and pigmentation correction in one.

CONCLUSION ON NOVORETIN™ IN SKINCARE

NovoRetin™ has established itself as an innovative retinol alternative that combines the benefits of classical retinoids with significantly improved tolerability. By increasing the skin’s own retinoic acid concentration, it works effectively against wrinkles, pigmentation spots, and blemishes – without putting excessive stress on the skin.

Clinical studies have shown that NovoRetin™ stimulates collagen production, smooths skin texture, and promotes a more even, youthful-looking complexion. Its plant-based origin and high formulation stability make it an active that is not only effective but also sustainably applicable.

Particularly in the retinol serums from DOC BERGER EFFECT, NovoRetin™ demonstrates its strength: supporting intensive yet gentle anti-aging care suitable for both beginners and experienced users.

Thus, NovoRetin™ represents a new generation of biotechnologically developed actives, combining anti-aging performance with high skin tolerability – making a valuable contribution to modern, effective, and gentle skincare.

Please note: NovoRetin™ is a registered trademark of Mibelle Biochemistry. This article is for informational purposes only and does not imply any business relationship with Mibelle Biochemistry.