Taff TV Test Winner Special

Hyper Hyaluron Serum

High-dose hyaluronic serum with peptide lifting effect

4.8/5
  • Test winner in taff's independent hyaluronic acid serum test

  • 17% less wrinkle depth in just 28 days

  • Botox®-inspired peptide technology (Acetyl-Hexapeptide-8 & SYN®-AKE) results in visibly more relaxed facial features

Regular Price
€248,00
Regular Price
€248,00
Sale Price
€223,20
Sold Out
Unit Price
Tax included. Shipping calculated at checkout.
€16.533,33perl
In stock – ships next business day.

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Note regarding the reviews

Regular Price
€248,00
Regular Price
€248,00
Sale Price
€223,20
Sold Out
Unit Price
Tax included. Shipping calculated at checkout.
€16.533,33perl

PURE EFFECT COSMETICS

Focus on What Matters Most

Triple Hyaluronic Acid for Intensive Moisture Binding

Absorbs quickly - ideal for layering with other serums

Non-comedogenic

With Next-Gen Peptides for visible smoothing of the skin surface

Ideal alternative/supplement to aesthetic treatments

Developed by a plastic surgeon in Munich

Real customer results

Before

After

after 3 months of consistent use

Everyone knows hyaluronic acid—but hyaluronic acid isn’t all the same. The key differences are the molecular sizes and their ability to bind moisture in different layers of the skin. Our Hyaluron Lifting Serum combines high‑molecular‑weight and low‑molecular‑weight hyaluronic acids so that not only the surface is intensely hydrated, but the overall moisture balance stays even. The result: no more dull skin, reduced fine dry lines, and a fresh, plump glow. Our day‑ and night creams were also used for this purpose.

Before

After

after 2 months of consistent use

SYN®‑AKE and ARGIRELINE™ are among the most advanced anti‑aging peptides. Both are included in our Hyaluron Lifting Serum and can visibly reduce existing wrinkles while slowing the formation of new fine lines. By specifically relaxing mimetic micro‑tensions, the skin surface smooths with consistent use. Ideal for anyone who wants to age naturally or who wants to boost the effect of their aesthetic treatments. A small tip: Our Hyaluron Lifting Serum pairs perfectly with the Vit C + Biobotox Serum.

-17%

reduction in wrinkle depth after just 28 days. Measured in the laboratory.

9+

high-quality active ingredients, precisely balanced to work together.

Hyper Hyaluron Serum

For your perfect skincare routine

Morning
Morning Time of day
All skin types Skin type

How to use

  • You can either use the Hyaluron Lifting Serum alone or mix it with the Vit C + Biobotox Serum and/or the Booster Serum. Simply mix the serums in the palm of your hand and gently pat into cleansed and toned skin on your face, neck and décolleté. Allow the serum to absorb into the skin for about 1 minute.
  • During the day you should then apply the Anti-Pollution Day Cream with a sun protection factor of at least 30 to ensure sufficient sun protection.
  • If you use the serum in the evening, please apply your usual night cream afterwards.

Complete your morning routine

Schritt 1 Cleansing
DOC BERGER EFFECT Foam Sensitive Reinigungsschaum für empfindliche und trockene Haut besonders sanft und beruhigend
Foam Sensitive

Gentle cleansing foam – for sensitive or dry skin

€32,00
Schritt 2 Activating
DOC BERGER EFFECT Tonic Sensitive Gesichtswasser für empfindliche und trockene Haut beruhigend und feuchtigkeitsspendend
Tonic Sensitive

Soothing Facial Tonic with Panthenol – for sensitive or dry skin

€35,00
Schritt 3 Firming
Aktuelle Auswahl
DOC BERGER EFFECT Hyper Hyaluron Serum – intensives Hyaluron Feuchtigkeitsserum mit Lifting Effekt für pralle, hydratisierte Haut
Hyper Hyaluron Serum

High-dose hyaluronic serum with peptide lifting effect

€248,00
Schritt 4 Abschwellend
DOC BERGER EFFECT Lifting Eye Wonder Augencreme gegen Schwellungen und feine Linien für eine glattere und strahlende Augenpartie
Lifting Eye Wonder

Refreshing eye fluid that improves the appearance of puffiness and fine lines.

€198,00
Schritt 5 Protecting
DOC BERGER EFFECT Four Seasons Day Cream mit SPF 50 und UVA Schutz für täglichen Anti Aging Schutz vor UV Strahlung und Hautalterung
Four Seasons Day Cream

Day cream with SPF 50+ and enhanced protection against blue light and infrared

€198,00

Stars trust DOC BERGER EFFECT

Chosen by leading women who don't compromise on their skin.

GLOBAL SUPERSTAR

Georgina Rodríguez

Millions of people follow Georgina Rodríguez – through international travel, the spotlight, family life and sport. International visibility also places high demands on the skin. This makes skincare that performs even under pressure all the more important. That is exactly what her DOC BERGER EFFECT favorites stand for.

SKINCARE FOR 40+

Katja Burkard

Katja Burkard (61) is one of Germany's best-known faces. The presenter and menopause expert supports women in midlife who want to maintain a naturally fresh appearance as they age. Her DOC BERGER EFFECT routine shows how high-quality active skincare can provide lasting support for skin over 40 and 50.

MODERN SKINFLUENCER

Leonie Hanne

Leonie Hanne stands for prevention rather than repair, and clean beauty without unnecessary extras. Starting early, consistently protecting the skin from the sun and providing intensive hydration to help prevent damage in the first place – that is what Leonie’s Beauty Essentials represent. Leonie values skincare with highly concentrated active ingredients, without unnecessary additives.

Dr. Luise Berger

A word from our founder

Do you feel like your skin is working against you? Moisture is lost, fine lines are digging in deeper, and every morning your face looks a little more tired. Maybe you've already tried aesthetic treatments and want to support their effect holistically. Or you prefer a natural, non‑invasive alternative because those procedures don't feel right for you. Either way: no problem. That's exactly where the Hyaluron Lifting Serum comes in — with two highly effective anti‑aging peptides that gently relax expression lines and can slow the formation of new ones.

Need help choosing your products?
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PERSONAL · ONE-TO-ONE

Skin expert Eleonora Berger

Personalized product advice

  • Talk to us live
  • Specific product recommendations
  • Tailored to your skin goals
Start your consultation
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DOC BERGER EFFECT Skin Analysis

Free online skin analysis

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OUR COMMITMENT

What makes DOC BERGER EFFECT cosmeceuticals special?

20 years of medical expertise. In every formula.

Dr. Luise Berger personally develops every formulation. For over 20 years, her daily work as a specialist in plastic and aesthetic surgery has focused on the skin and how it ages. This expertise goes into every formula – with the aim of preserving skin quality over the long term and improving it through targeted care.

Clean. Without compromise. Made in Germany.

Simply avoiding a few controversial ingredients is not enough for us. DOC BERGER EFFECT is always free from: alcohols, silicone oils, paraffins, PEGs/PPGs, parabens, microplastics, nanoparticles, colorants, potentially allergenic fragrances and UV filters of concern. This makes development considerably more complex – but for you, we keep refining our formulas until they work without them. After all, the skin is our largest organ, and what we apply to it every day matters. Developed and manufactured in Germany.

A wealth of active ingredients at the highest concentrations

More than a single hero ingredient: over 100 active ingredients from nature and biotechnology research, precisely balanced to work together. At the highest concentrations and designed as a skincare system, with more active ingredients per milliliter and products that complement each other.

  • 5 stars: 99 (85%)
  • 4 stars: 13 (11%)
  • 3 stars: 3 (3%)
  • 2 stars: 1 (1%)
  • 1 star: 0 (0%)
M
Martina Z.
Die sind der Hammer!

Ich liebe einfach ALLE eure Produkte! Ich wende jetzt alles, wie von der lieben Eleonora aus der virtuellen, pers. Beratung vorgeschlagen, an, und habe das Gefühl, die Haut sieht echt glatter und aufgepolsterter aus 🙏 Danke für den top Service mit der Beratung 🥰 mein Lieblingsserum ist das Hyaluron Serum mit den Botox-Peptiden, in Kombination mit dem Platinum Serum am Abend - macht echt süchtig😍

K
Karin Freitag
Fühlt sich einfach stimmig an

Ich habe wirklich viele Marken ausprobiert – auch Doctor Brands wie Dr. Sturm oder Dr. Emi.
Aber gerade mit reiferer Haut habe ich gemerkt, dass mir das oft nicht ausreicht. Für echtes Anti-Aging und vor allem Skin Longevity braucht es einfach mehr als nur „gute Pflege“.
Und genau das habe ich bei DOC BERGER EFFECT gefunden. Die Wirkstoffe und vor allem die Kombinationen sind auf einem ganz anderen Level – man merkt, dass hier eine plastische Chirurgin dahintersteckt: mehr Spannkraft, mehr Ausstrahlung und dieses „satte“, gesunde Hautgefühl. Für mich wirklich ein absoluter Unterschied – gerade ab 40.

C
Caroline Hartmann
Endlich dieser natürlicher Glow, auf den ich angesprochen werde

Ich werde in letzter Zeit so oft auf mein Strahlen angesprochen. Natürlich habe ich meine Haut schon immer gepflegt, aber so etwas habe ich wirklich noch nie erlebt – dass mich mein Umfeld plötzlich darauf anspricht und mir Komplimente macht.
Ich bin 48 Jahre alt und mir ist Natürlichkeit sehr wichtig. Ich möchte also nicht auf Teufel komm raus jede Falte bekämpfen, sondern einfach frischer aussehen und meiner Haut etwas Gutes tun – ohne Injektionen oder OPs beim Beauty-Doc.
Deshalb habe ich die Wirkstoffkosmetik von Doc Berger ausprobiert und speziell dieses Hyaluron Serum ist für mich ein absoluter Traum.
Ich hasse es nämlich, wenn herkömmliche Feuchtigkeitsseren so klebrig sind oder einen glänzenden Film hinterlassen. Dieses hier ist komplett anders: Es zieht sofort ein und hinterlässt einfach nur das Gefühl von richtig durchfeuchteter, glatter Haut.
Meine Stirnfältchen sind nach etwa vier Wochen tatsächlich schon feiner geworden. Ich bin wirklich verliebt! Als Nächstes werde ich es noch mit dem Doc Berger Collagen Serum kombinieren 😍

A
Andrea Lorenz
Einfach nur toll!🥹

Ich bin begeisert! Nutze das Serum nun schon seit ca einem Jahr - meine Haut wird super gepflegt und das Serum polstert super auf! Habe ebenfalls das Gefühl, dass sich durch die tägliche Anwendung fast keine Falten anfangen zu bilden.

M
Marina Zimmer
Tolles Produkt, täglich in Benutzung

Das Hyaluron Lifting Serum hat eine sehr wässrige Konsistenz, lässt sich also super auftragen und zieht direkt ein. Meine Haut ist seitdem einfach wirklich glatter und meine trockenheitsfältchen weg. Nutze es noch in Kombi mit dem Vit C Biobotox Serum. Bin einfach begeistert. 🙂‍↔️

C
Carla S.
Bestes Hyaluron Serum

Ich habe viiiiele verschiedene ( teure ! ) Hyaluron Seren ausprobiert, das von DOC BERGER ist mit Abstand das BESTE! Sowieso alles von DOC BERGER EFFECT ist unfassbar toll und wirkt genau so wie es soll. Ich habe nun meine ganze Pflegeroutine auf DOC BERGER umgestellt und meine Haut war noch nie so schön ->Unreine Haut mit Pigmentflecken und erste Fältchen 🥲 mit dieser Skincare aber nun Welten besser !! Ich brauche sogar an den meisten Tagen kein Make up mehr 🥳 Danke DOC BERGER, ihr hält was ihr verspricht 🫶🏼🙏🏼

O
Olivia Haas
Frisch in den Tag

Ehrlich gesagt finde ich alle Produkte von DOC BERGER super, das Hyaluron Lifting Serum aber ganz besonders. Ganz leicht auf der Haut, spendet Feuchtigkeit und gerade im Winter mit der ganzen Heizungsluft ein Muss. Manchmal gebe ich auch ein ganz bisschen extra auf die Lippen, die dann gut durchblutet werden und es hat einen kleinen Pump-Effekt.

J
Jeannette S.

Bei vielen Seren hatte ich nacher nie das Gefühl meine Haut fühle sich durchfeuchtet an. Mit diesem habe ich endlich ein WOW Effekt.! 10/10 :-)

P
Petra Dietz
Leicht wie Wasser – und so wirksam

Die Textur ist unglaublich leicht und fast wässrig – überhaupt nicht klebrig oder schwer auf der Haut. Genau das mag ich besonders. Trotz dieser leichten Konsistenz merkt man richtig, wie viel Feuchtigkeit die Haut bekommt. Meine Haut saugt alles auf wie ein Schwamm. Besonders schön finde ich, dass Peptide enthalten sind, die kleine Fältchen sichtbar entspannen können. Doc Berger erklärt das immer perfekt auf Instagram und ist so sympathisch!
Für mich ist das inzwischen ein fester Bestandteil meiner Routine geworden – gerade morgens liebe ich dieses frische, durchfeuchtete Hautgefühl.

S
Sarah Mitchell
Favourite hyaluronic acid serum

I have tried a few different brands and this one still comes out on top - I also bought Docberger Platinum Elixir and Collagen Serum and they are amazing.✨

A
Anonym

Gefällt mir sehr gut. Zieht schnell ein und hinterlässt keinen Film sodass man super danach die tagespflege auftragen kann.

J
Jane E.

Ich kaufe regelmäßig bei doc berger effect, die Produkte sind alle sehr gut 😍 Bin sehr zufrieden.

L
Lilli
😍

Für mich einfach das beste Hyaluron Serum. Die Haut wird wirklich schön durchfeuchtet und geglättet.👍

Y
Yasmin Lang

Bewährte Begleiter seit Jahren! Möchte nicht mehr darauf verzichten!😇❣️

G
Greta Dreyer
Unverzichtbar

Ich habe das Hyaluron Lifting Serum bereits zum zweiten Mal gekauft und bin sehr zufrieden. Es ist ein hochwertiges Produkt, das meine Haut intensiv mit Feuchtigkeit versorgt, ohne zu beschweren. Ich kann es mit gutem Gewissen weiterempfehlen.

G
G.R.

En l’appliquant sur une peau légèrement humide,le résultat est flagrant. De loin le meilleur soin à l’acide Hyaluronique.

A
Amira Ziegler
Sehr zufrieden!😍

Spendet gut Feuchtigkeit, ohne die Haut fettig zu machen, sehr effektiv mit nur wenigen Tropfen.

Z
Zoe Wegner

Polstert die Haut gut auf und fühlt sich toll an.

D
D.F.

Sehr angenehm und wohltuend auf der Haut, zieht schnell ein, sehr gut verträglich, für die reifere Haut bestens geeignet.

M
Manuela Greco
👏👏👏

Eines der Seren, die ich am meisten liebe. Seit ich es benutze, bald zwei Monate, habe ich keine Trockenheit mehr, meine Haut ist weicher und mein Teint stark verbessert. Ich kann es nur empfehlen.

E
Eva Berg
Mega

Ich liebe Doc Berger Effect Skincare, werde ich immer wieder nachkaufen und meine Haut ist so viel besser geworden.🤗🤗

A
Anonymous

Richtig angenehmes Hautgefühl

A
Anonymous
Fühlt sich an wie ein großer Schluck Wasser für die Haut 💦

Ich bin echt kein Morgenmensch, aber mit diesem Serum sieht meine Haut morgens viel erholter aus. Selbst wenn ich nur fünf Stunden geschlafen hab, wirkt meine Haut irgendwie „plumper“ (im positiven Sinne 😆).

A
Anonymous

Mein Geheimtipp für den Winter ❄️

A
Anonymous

Es gibt nix Schlimmeres als Seren, die sich so komisch pappig anfühlen… Aber das hier? Zieht total schnell ein und macht meine Haut einfach nur weich und „aufgepolstert“. Ich benutze es unter meiner Tagescreme und das Make-up sitzt viel schöner.

A
Anonymous
Hätte nicht gedacht, dass es SO gut funktioniert!

Perfekt für meine feuchtigkeitsarme Haut

A
Anonymous
Neues Lieblingsserum

Ganz ehrlich, ich dachte zuerst, naja, ein Hyaluron-Serum halt, hab schon viele probiert… Aber DAS hier ist anders. Meine Haut ist super durchfeuchtet, kleine Fältchen an den Augen und der Stirn sind fast weg und ich seh einfach frischer aus. Hab’s schon meiner Mama empfohlen! 😆

A
Anonymous

Ich benutze es jeden Morgen & Abend – süchtig! 🙈

A
Anonymous

Ich seh morgens direkt wacher aus! 🌞

A
Anonymous

Wollte es eigentlich nur abends nutzen, aber meine Haut liebt es so sehr, dass ich es morgens direkt nochmal auftrage. Sie fühlt sich den ganzen Tag gepflegt an und wirkt so prall und frisch. Kann nicht mehr ohne!

FAQs

Hyaluronic acid is a natural substance found in the human body and has excellent moisture-binding properties. What's unique about hyaluronic acid in serums is its ability to bind up to a thousand times its weight in water. This makes it one of the most effective moisturizers in skincare. This is especially important for maintaining the elasticity and flexibility of the skin.

The Hyaluron Lifting Serum is a must-have in any anti-aging skincare routine. It is suitable for all skin types, but particularly recommended for dry and sensitive skin.

After cleansing with the corresponding Foam and applying a Tonic, gently pat a few drops of the serum into your face. You can then proceed with your eye care routine (morning: primarily the Lifting Eye Wonder, evening: primarily the Eye Cream) and use your regular day or night cream.

For optimal results, we recommend daily use, primarily in the morning but also in the evening if desired.

Yes, the serum can be easily combined with other serums. In the morning, for example, combine it with the Vitamin C + Biobotox Serum or the Booster Serum. In the evening, you can combine it with the Vitamin C + Biobotox Serum , the Booster Serum , the Purifying Power Serum or the Red & Pigment Remover.

To repair sun damage, gently pat the Hyaluron Lifting Serum mixed 1:1 with the Vitamin C + Biobotox Serum into your skin. Then, apply the Night Cream Rich generously. Valuable antioxidants help neutralize the free radicals caused by UV radiation and restore the moisture balance of your skin.

The time it takes to see results can vary from person to person, but many users report noticeable improvements in skin texture and hydration within just a few days of use. However, it's recommended to plan for at least 2-3 months to achieve visible results. Why? Because your skin needs time to absorb the active ingredients, undergo regeneration from the ground up, and naturally produce more collagen, elastin, and other essential building blocks.

Important information for your travels:

Our active ingredient serums have been carefully developed to support your daily skincare routine. However, please be aware that during travel – especially on flights – there is a risk that the serums may leak due to pressure changes or movement. Unfortunately, we cannot assume liability for such incidents.

To minimize the risk of leakage, we recommend the following steps:

1. Check the seal:

Before your trip, make sure all lids and closures are securely tightened. We recommend removing the pipette once and carefully wiping the neck of the bottle with a tissue to remove any residue. This is often the spot where leaks may occur. Only after cleaning should the pipette be screwed back on tightly.

2. Store upright:

Keep the products in an upright position whenever possible.

3. Carry in hand luggage:

When flying, carry the products in your hand luggage to better control storage conditions.

If you have any concerns, we recommend leaving the serums at home as a precaution to avoid potential leakage altogether.

Dr. Luise Berger und Eleonora Berger
DOC BERGER EFFECT Hyper Hyaluron Serum mit Hyaluronsäure und dem botoxartig wirkenden Peptid Syn-Ake® – intensives Peptid Serum gegen Falten, Trockenheitslinien und Feuchtigkeitsverlust für glatter und praller wirkende Haut ab 40 und 50.

Hyper Hyaluron Serum

Three sizes of hyaluronic acid for intense hydration and visibly plumper skin

The Hyper Hyaluron Serum combines high-molecular-weight, low-molecular-weight and oligo hyaluronic acid to thoroughly hydrate the skin. Hyaluronic acid can bind many times its own weight in water, helping the skin retain moisture. The result: fuller, more supple and plumper-looking skin.

DOC BERGER EFFECT Hyper Hyaluron Serum mit Syn-Ake® Peptid und Hyaluronsäure – Peptide gegen Falten und Trockenheitslinien für intensive Feuchtigkeit, glatter wirkende Haut und einen sichtbaren Anti-Aging- und Lifting-Effekt.

Hyper Hyaluron Serum

Botox-like peptides smooth expression lines

Acetyl Hexapeptide-8 and SYN®-AKE add a targeted anti-aging effect. These Botox-like peptides ("neuropeptides") can make expression lines appear more relaxed and smoother and help prevent them from deepening. The serum therefore targets not only dehydration lines, but also expression lines. Independent studies show that just 15 minutes after application, wrinkle depth was reduced by an average of 6%. With continued use, this effect increased to 8% after 14 days and an impressive 17% after 28 days – demonstrating the benefits of a hyaluronic acid peptide serum.

DOC BERGER EFFECT Hyper Hyaluron Serum als feuchtigkeitsspendendes Peptid Serum mit Syn-Ake® – botoxartiges Peptid gegen Falten kombiniert mit mehrstufiger Hyaluronsäure für intensive Hydration, ein aufgepolstertes Hautgefühl und glatter wirkende Mimikfalten.

Hyper Hyaluron Serum

Soothe, protect and refresh your skin whenever it needs it

Niacinamide, aloe vera and green tea complete this concentrated hyaluronic acid serum with soothing, strengthening and antioxidant properties. This makes Hyper Hyaluron Serum an essential daily hydration and anti-aging boost – especially when traveling, when dry air, changes in climate or long flights put additional strain on the skin. In a TV test by taff (ProSieben), the DOC BERGER EFFECT hyaluronic acid serum with peptides stood out and was named the winner in the "peptide serum" / "hyaluronic acid serum" comparison.

Your skin tells your story – let it be one of love.

Peptide Serum for Wrinkles: Advanced Neuropeptides
Meet Intensive Hyaluronic Acid Skincare – DOC BERGER EFFECT®

The Hyper Hyaluron Serum was developed for skin that needs intensive hydration combined with targeted anti-aging care for expression lines. Our formula combines hyaluronic acid at the highest concentration with advanced peptides for wrinkles to help skin look plumper, smoother, and visibly more relaxed – ideal for demanding skin that wants more than a conventional hyaluronic acid serum.

Who is the Hyper Hyaluron Serum suitable for?

Our hyaluronic acid peptide serum is ideal if:

✓ You want a smoother, fresher appearance

Expression lines on your forehead, around your eyes, or around your mouth are becoming increasingly visible

✓ Your skin looks dehydrated, dry, or less plump

✓ You want to add targeted wrinkle-fighting ingredients to your skincare routine, both to prevent and address wrinkles

With its lightweight, fast-absorbing formula, the peptide serum is suitable for different skin types and can be used morning and evening, as well as alongside other serums and creams.

Peptide Serum Benefits: What Can Hyaluronic Acid & Peptides Do for Wrinkles?

The Hyper Hyaluron Serum by Doc Berger Effect targets the processes behind visible skin aging, combining intensive hydration from hyaluronic acid with targeted relief of expression lines through advanced neuropeptides.

Peptides for Forehead Lines, Frown Lines, and Crow's Feet

Peptides are short chains of amino acids used in skincare as
targeted messengers.
Depending on the peptide, they can support different skin processes, including skin structure, collagen production and regeneration, or the visible smoothing of fine lines and wrinkles.

The Hyper Hyaluron Serum contains two specific anti-aging peptides that are particularly relevant for expression lines on the forehead, between the eyebrows, and around the eyes and mouth. They target the mechanisms through which repeated muscle movements lead to visible lines, helping create a smoother, more relaxed-looking complexion. This specific group is known as neuropeptides (Botox-like peptides).

Neuropeptides for Fine Expression Lines

Certain biomimetic peptides are often called neuropeptides or neuroactive peptides in cosmetics because their approach targets processes associated with expression-related tension ("Botox-like"). In the Hyper Hyaluron Serum
by DOC BERGER EFFECT, Acetyl Hexapeptide-8 (Argireline®) and SYN®-AKE fulfill this role. They are particularly suitable for areas where repeated facial expressions can leave visible lines over time.

Intensive Plumping with Hyaluronic Acid for Fine Lines Caused by Dryness

Hyaluronic acid has an exceptional ability to bind water. It provides intensive hydration, leaving skin feeling softer and plumper. Fine lines caused by dehydration can therefore appear less noticeable.

Supporting the Skin Barrier

Niacinamide, panthenol, and aloe vera complement the highly concentrated hyaluronic acid serum with soothing and caring properties – important for helping the skin retain moisture more effectively over time.

Antioxidant Protection

Green tea adds protection against oxidative stress to the peptide serum, helping shield the skin from harmful environmental influences.

Argireline™ in a Peptide Serum – Targeted Care for Expression Lines

Argireline™ (Acetyl Hexapeptide-8) is one of the best-known peptides for expression lines. Unlike Botox, Argireline™ is applied topically to the skin. The peptide targets processes associated with facial muscle activity without completely immobilizing the muscles – natural facial expressions are preserved. The ingredient is also considered very well tolerated and suitable for all skin types.

In the Hyper Hyaluron Serum, Argireline™ is combined with highly concentrated hyaluronic acid: Hyaluronic acid provides intensive hydration, while Argireline™ specifically targets fine expression lines.

SYN®-AKE – A Second Neuropeptide for Expression Lines

SYN®-AKE is a biomimetic neuropeptide whose mechanism is inspired by the snake venom peptide Waglerin-1 . It targets processes associated with facial muscle activity and can help visibly smooth expression lines and counteract their further progression.

What makes the Hyper Hyaluron Serum special: We use not just one, but two highly concentrated neuropeptides – SYN®-AKE and Argireline™ (Acetyl Hexapeptide-8). Together, they create a particularly potent peptide combination for expression-related lines and wrinkles.

The effectiveness of the complete formula was independently examined by an external laboratory: after just 15 minutes, wrinkle depth was reduced by 6%, after 14 days by 8%, and after 28 days by 17%. The serum therefore combines intensive hydration with a measurable anti-aging effect on wrinkles.

Which Peptides Have Botox-Like Effects or Are Considered Alternatives to Botox?

Neuropeptides such as Argireline™ (Acetyl Hexapeptide-8) and SYN®-AKE are commonly described as "Botox-like peptides." They target processes associated with facial muscle activity and can help visibly smooth expression lines such as forehead lines, frown lines, and laugh lines. They do not replace a Botox injection, but skincare customers often refer to them as a "Botox alternative" or "complement to Botox." These peptide serums are particularly popular with people who choose to age naturally and avoid injections or surgical procedures. Highly effective peptide serums can offer a non-invasive way to target signs of skin aging.

For those who choose aesthetic treatments, peptides can be used as a gentle complement to a comprehensive anti-aging routine to help support skin quality and a fresh, smooth overall appearance over time.

How to Use the Hyper Hyaluron Peptide Serum

The peptide serum is primarily used in the morning after cleansing and toning the skin.

Apply a few drops to half a dropper of serum to your face, neck, and décolleté, gently patting it into the skin. Allow about one minute for it to absorb.

The Hyper Hyaluron Serum can be used alone or combined with other DOC BERGER EFFECT serums – it works particularly well alongside the Vit C + Spilanthol Serum in your skincare routine.

Morning: After applying the Hyper Hyaluron Serum, follow with a day cream offering sufficient sun protection, such as our Four Seasons Day Cream with SPF 50+.

Want to intensify the effect?

Use it in the evening as well:
After the serum, finish your skincare routine with an anti-aging night cream, such as our Time Machine.

With its lightweight texture, the Hyper Hyaluron Serum layers particularly well and is suitable for regular use as a hydrating anti-aging peptide serum.

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